DRUGS WITH SEDATIVE PROPERTIES – HOW THEY AFFECT THE BODY

2. Histamine Receptor Antagonism: Some sedatives, for instance antihistamines, exert their sedative effects by blocking histamine receptors in the Mind, particularly H1 receptors. Histamine plays a role in wakefulness and arousal, so blocking its effects encourages sedation and sleepiness.Medical professionals and veterinarians often administer sed